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GNE-4997

CAT: 0931-T15402-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T15402-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1705602-02-3
Target
Others, Tyrosine Kinases
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM) . The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.
Smiles
C[C@@]12[C@@](C1(F)F)(CC3=C(C2)NN=C3C(NC4=CN([C@@H]([C@@]5(S(=O)(=O)CCCC5)[H])C6=CC=CC=C6)N=C4)=O)[H]
Molecular Formula
C25H27F2N5O3S
Molecular Weight
515.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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MBS3842163-01GNE-4997
A17188-50GNE-4997 50mg
A17188-5GNE-4997 5mg
A17188-10GNE-4997 10mg
MBS131349Selonsertib (GS-4997; GS4997; GS 4997)
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S8292-100mgSelonsertib (GS-4997)
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