Products for Research Use Only
RegisterLogin

Gemcitabine elaidate

CAT: 0931-T15378-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T15378-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
210829-30-4
Target
Autophagy, Nucleoside Antimetabolite/Analog, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Autophagy
Bioactivity
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.
Smiles
CCCCCCCC\C=C\CCCCCCCC(=O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C(F)(F)[C@@H]1O
Molecular Formula
C27H43F2N3O5
Molecular Weight
527.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
TCL-00162-01Cholesteryl elaidate
TN6999-01Methyl elaidate
T0251-01Gemcitabine
TCL-00202-014-Methylumbelliferyl elaidate
T6069-01Gemcitabine hydrochloride
T21329Gemcitabine monophosphate
T75252-01Gemcitabine triphosphate
TYD-02519-01MC-VC-PAB-O-Gemcitabine
T4187-01Gemcitabine monophosphate sodium salt hydrate
TMIJ-0190-01Gemcitabine EP Impurity C-13C-15N2

Alternative Products

CatalogName
C03494Gemcitabine elaidate
GTR19156279-01Gemcitabine (elaidate)
MBS3613610-01Gemcitabine(elaidate)
A13693-5Gemcitabine elaidate 5mg
BUP01386-01Gemcitabine elaidate hydrochloride
A13693-50Gemcitabine elaidate 50mg
NC05399-01Gemcitabine 5'-elaidate
A13693-25Gemcitabine elaidate 25mg
A13693-10Gemcitabine elaidate 10mg
HY-13538A-01Gemcitabine elaidate (hydrochloride)

Popular Products