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Fluorofenidone

CAT: 0931-T15300-06Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T15300-06Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
848353-85-5
Target
Akt, PI3K, Others
Related Pathways
PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling
Purity
0.9987
Bioactivity
Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
Smiles
Cc1ccc(=O)n(c1)-c1cccc(F)c1
Molecular Formula
C12H10FNO
Molecular Weight
203.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Fluorofenidone
CAS Number848353-85-5
PubChem CID11851183
IUPAC Name1-(3-fluorophenyl)-5-methylpyridin-2-one
Molecular FormulaC12H10FNO
Molecular Weight203.21
XLogP2
Topological Polar Surface Area20.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count15
Formal Charge0
Complexity322
SMILES
CC1=CN(C(=O)C=C1)C2=CC(=CC=C2)F
InChI
InChI=1S/C12H10FNO/c1-9-5-6-12(15)14(8-9)11-4-2-3-10(13)7-11/h2-8H,1H3
InChIKey
JDZYVVUJIQYGRX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Fluorofenidone
CAS: 848353-85-5
CID: 11851183
Formula: C12H10FNO
MW: 203.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight203.21
XLogP32
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass203.074642105
Monoisotopic Mass203.074642105
Topological Polar Surface Area20.3 Ų
Heavy Atom Count15
Formal Charge0
Complexity322
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
527487Fluorofenidone
HY-121246R-01Fluorofenidone (Standard)
RM-F500002-01Fluorofenidone-D3
RM-F500003-01Fluorofenidone Impurity 3
RM-F500001-01Fluorofenidone Impurity 1
AR-F01730-01Fluorofenidone Impurity 2
RM-F500005-01Fluorofenidone Impurity 5
AR-F01731-01Fluorofenidone Impurity 2-d3
RM-F500006-01Fluorofenidone Impurity 5-D3
HY-143956S-01Fluorofenidone impurity 1-d3

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