(±) -10-Hydroxycamptothecin

• Target:

  Topoisomerase

• Related Pathways:

  DNA Damage/DNA Repair

• Purity:

  0.9958

• Bioactivity:

  (±) -10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

• Smiles:

  CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O

• Molecular Formula:

  C20H16N2O5

• Molecular Weight:

  364.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  64439-81-2