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DBCO-NHCO-PEG4-amine

CAT: 0931-T15062-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15062-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1255942-08-5
Target
ADC Linker, PROTAC Linker
Related Pathways
PROTAC, Antibody-drug Conjugate/ADC Related
Bioactivity
DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].
Smiles
O=C(NCCC(=O)N1C=2C=CC=CC2C#CC=3C=CC=CC3C1)CCOCCOCCOCCOCCN
Molecular Formula
C29H37N3O6
Molecular Weight
523.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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