Elexacaftor

• Target:

  Autophagy|||CFTR

• Related Pathways:

  Autophagy|||Membrane transporter/Ion channel

• Purity:

  0.9987

• Bioactivity:

  Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It promotes the processing and trafficking of CFTR, increases the amount of CFTR on the cell surface, and improves the processing and trafficking of Phe508del CFTR protein.

• Smiles:

  C(NS(=O)(=O)C1=CN(C)N=C1C)(=O)C2=C(N=C(C=C2)N3N=C(OCC(C(F)(F)F)(C)C)C=C3)N4C[C@@H](C)CC4(C)C

• Molecular Formula:

  C26H34F3N7O4S

• Molecular Weight:

  597.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2216712-66-0