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Ciclopirox

CAT: 0931-T1482-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T1482-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
29342-05-0
Target
Antifungal|||Autophagy|||ATPase|||Ferroptosis|||Antibacterial
Related Pathways
Microbiology/Virology|||Apoptosis|||Autophagy|||Membrane transporter/Ion channel
Purity
0.9978
Bioactivity
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX) .
Smiles
ON1C(=CC(C)=CC1=O)C2CCCCC2
Molecular Formula
C12H17NO2
Molecular Weight
207.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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