Ciclopirox

• Target:

  Antifungal|||Autophagy|||ATPase|||Ferroptosis|||Antibacterial

• Related Pathways:

  Microbiology/Virology|||Apoptosis|||Autophagy|||Membrane transporter/Ion channel

• Purity:

  0.9978

• Bioactivity:

  Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX) .

• Smiles:

  ON1C(=CC(C)=CC1=O)C2CCCCC2

• Molecular Formula:

  C12H17NO2

• Molecular Weight:

  207.27

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  29342-05-0