BMS-248360

• Target:

  Endothelin Receptor|||RAAS|||Others

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones|||Others

• Bioactivity:

  BMS-248360 is a potent, orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor, with Kis of 10 nM and 1.9 nM for hAT1 and hETA receptors, respectively. BMS-248360 demonstrates hypertensive effects[1].

• Smiles:

  O=C1C2(N=C(CCCC)N1CC3=CC(CN4C(=O)C(C)(C)CC4)=C(C=C3)C5=C(S(NC6=C(C)C(C)=NO6)(=O)=O)C=CC=C5)CCCC2

• Molecular Formula:

  C36H45N5O5S

• Molecular Weight:

  659.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  254737-87-6