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BMS-248360

CAT: 0931-T14672-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T14672-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
254737-87-6
Target
Endothelin Receptor, RAAS, Others
Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Others
Bioactivity
BMS-248360 is a potent, orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor, with Kis of 10 nM and 1.9 nM for hAT1 and hETA receptors, respectively. BMS-248360 demonstrates hypertensive effects[1].
Smiles
O=C1C2(N=C(CCCC)N1CC3=CC(CN4C(=O)C(C)(C)CC4)=C(C=C3)C5=C(S(NC6=C(C)C(C)=NO6)(=O)=O)C=CC=C5)CCCC2
Molecular Formula
C36H45N5O5S
Molecular Weight
659.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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