BI-671800

CAT: 0931-MF-0006288-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0006288-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1093108-50-9
Target
Prostaglandin Receptor|||GPCR
Related Pathways
Immunology/Inflammation|||Endocrinology/Hormones|||GPCR/G Protein
Purity
0.9919
Bioactivity
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) . With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].
Smiles
CN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(O)=O
Molecular Formula
C25H26F3N5O3
Molecular Weight
501.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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BA5725-25BI-671800
A18902-1BI-671800 1mg
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A18902-100BI-671800 100mg
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A18902-50BI-671800 50mg
A18902-5BI-671800 5mg
A18902-25BI-671800 25mg
A18902-10mM-DBI-671800 10mM * 1mL in DMSO
B2798-500BI

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