BI 7446

• CAS Number :

  2767011-00-5

• Target :

  STING

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  BI 7446 is a potent and selective cyclic dinucleotide (CDN) -based stimulator of interferon genes (STING) agonist capable of activating all five STING variants in cells, thus inducing tumor-specific immune-mediated tumor rejection. This compound is utilized in immuno-oncology research [1].

• Smiles :

  OC1[C@@]2([C@@H](O[C@@]1(COP(=O)(S)O[C@@]3([C@@](COP(=O)(S)O2)(O[C@H]([C@@H]3F)N4C=5C(N=C4)=C(N)N=CN5)[H])[H])[H])N6C7=C(N=C6)C(=O)NN=C7)[H]

• Molecular Formula :

  C20H22FN9O10P2S2

• Molecular Weight :

  693.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C