BI-4924

• Target:

  Dehydrogenase

• Related Pathways:

  Metabolism

• Purity:

  0.9955

• Bioactivity:

  BI-4924 is a selective and potent inhibitor of phosphoglycerate dehydrogenase (PHGDH) (IC50=3 nM) that disrupts serine biosynthesis by intracellular trapping, and can be used in the study of diseases caused by dysfunction.

• Smiles:

  Cc1cc2n(C)c(cc2c(Cl)c1Cl)C(=O)N[C@H](CO)c1ccc(cc1)S(=O)(=O)CC(O)=O

• Molecular Formula:

  C21H20Cl2N2O6S

• Molecular Weight:

  499.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2244452-09-1