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MLN-4924

CAT: 0026-2566-500Size: 500 µgDry Ice: NoHazardous: No
CAT#:0026-2566-500Size:500 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective inhibitor of NEDD8 (Neural precursor cell expressed, developmentally down-regulated 8)-activating enzyme (NAE) (IC₅₀ = 4.7 nM) with potential anticancer activity. NAE activates NEDD8, an ubiquitin-like (UBL) protein that modifies cellular targets in a pathway that is parallel to but distinct from the ubiquitin-proteasome pathway (UPP). Supresses the growth of tumor xenografts in mice.
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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