BAY 60-6583

• CAS Number :

  910487-58-0

• Target :

  Adenosine Receptor

• Related Pathways :

  Neuroscience|||GPCR/G Protein

• Purity :

  0.998

• Bioactivity :

  BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3 receptors.BAY 60-6583 is cardioprotective in a model of myocardial ischemia.The Ki values for BAY 60-6583 binding to mouse, rabbit, and dog A2BAR were 750 nM, 340 nM, and 330 nM, respectively. The Ki values of BAY 60-6583 binding to A2BAR in mice, rabbits and dogs were 750 nM, 340 nM and 330 nM respectively.

• Smiles :

  NC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC3CC3)cc2)c1C#N

• Molecular Formula :

  C19H17N5O2S

• Molecular Weight :

  379.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C