ARP-100

CAT: 0931-T14322-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T14322-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
704888-90-4
Target
MMP
Related Pathways
Proteases/Proteasome
Purity
0.9834
Bioactivity
ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM) . ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 ?M), MMP-3 (4.5 ?M), MMP-7 (>50 ?M) and MMP-9 (0.2 ?M) [1][2].
Smiles
CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1
Molecular Formula
C17H20N2O5S
Molecular Weight
364.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C