Products for Research Use Only
RegisterLogin

ARP

CAT: 0931-TYD-00896-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TYD-00896-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
139585-03-8
Bioactivity
ARP (Aldehyde reactive probe) is a chemical compound that serves as an aldehyde-reactive probe by specifically tagging AP sites in DNA with biotin residues. It is used to detect abasic sites, which are common forms of DNA damage and intermediates in mutagenesis and carcinogenesis. ARP is highly sensitive, capable of detecting abasic sites at the femtomolar level (fewer than 1 site per 10^4 nucleotides) .
Smiles
NOCC(NNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O
Molecular Formula
C12H21N5O4S
Molecular Weight
331.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

O-(Biotinylcarbazoylmethyl)hydroxylamine

formed by reacting biotin hydrazide with O-(carboxymethyl)hydroxylamine in the presence of carbodiimide; used to tag AP sites in damaged DNA with biotin; structure given in first source

CAS Number139585-03-8
PubChem CID83922
IUPAC Name5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N'-(2-aminooxyacetyl)pentanehydrazide
Molecular FormulaC12H21N5O4S
Molecular Weight331.39
XLogP-1.3
Topological Polar Surface Area160
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Heavy Atom Count22
Formal Charge0
Complexity436
SMILES
C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NNC(=O)CON)NC(=O)N2
InChI
InChI=1S/C12H21N5O4S/c13-21-5-10(19)17-16-9(18)4-2-1-3-8-11-7(6-22-8)14-12(20)15-11/h7-8,11H,1-6,13H2,(H,16,18)(H,17,19)(H2,14,15,20)/t7-,8-,11-/m0/s1
InChIKey
KYHUBFIOWQTECH-LAEOZQHASA-N
Chemical Structure
2D Structure
2D structure of O-(Biotinylcarbazoylmethyl)hydroxylamine
CAS: 139585-03-8
CID: 83922
Formula: C12H21N5O4S
MW: 331.39
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight331.39
XLogP3-1.3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass331.13142534
Monoisotopic Mass331.13142534
Topological Polar Surface Area160 Ų
Heavy Atom Count22
Formal Charge0
Complexity436
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
TMAB-02839-01Anti-ARP3 Polyclonal Antibody
TMAB-02838-01Anti-ARP2 Antibody (2V688)
TMAB-02837-01Anti-ARP2 Polyclonal Antibody
TMAH-00021-01Anti-Arp3/ACTR3 Antibody (2D811)
TMAC-00273-01Anti-Arp3/ACTR3 Antibody (1Q436)
TMPH-04709-01Arp3/ACTR3 Protein, Human, Recombinant (His)
TMPY-00358-01Arp3/ACTR3 Protein, Human, Recombinant (His & GST)
TMPH-03595-01ARPT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)
TMPH-00663-01ARPT Protein, E. coli O139:H28, Recombinant (His & Myc)

Alternative Products

CatalogName
303-150Riboclear (RNA Cleanup)
TBS10485-100Tribio InVivoMAb Anti-Mouse TIGIT & PD-L1 Bispecific Antibody
TBS10191-1mgTetrahydrocannabinol (THC) Monoclonal Antibody
TBI3024-25MGAc-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor
122-101ExgeneTM Forensic SV mini
TBS10483-100Tribio InVivoMAb Anti-Mouse PD-L1 & CD28 Bispecific Antibody
TBS10183-1mgMonoclonal Anti-Thyroid Stimulating Hormone (TSH) Antibody
TBS10340-0.5MGInVivo Mouse IgG1 Isotype Control Antibody
121-220Exfection Plasmid EF (Exdotoxin Free, Midi)
TBS10482-100Tribio InVivoMAb Anti-Mouse PD-L1 & OX40 Bispecific Antibody

Popular Products