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TR-100

CAT: 0931-T210006-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T210006-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1128165-86-5
Target
Arp2/3 Complex
Related Pathways
Cytoskeletal Signaling
Bioactivity
TR-100 is a small molecule inhibitor targeting tumor-associated tropomyosin (Tpm) . It binds to the C-terminus of Tpm3.1, affecting its interaction with actin filaments and thus influencing their stability and function. This mechanism allows TR-100 to specifically affect actin filament bundles in cancer cells without impairing cardiac muscle function. TR-100 is useful for studying the role of Tpm3.1 in cancer cell proliferation and survival, as well as its impact on insulin-stimulated glucose uptake and insulin secretion.
Smiles
N#CC(=CC=1C=2C=CC=CC2N(C1C)CCCN(C)C)C(=O)NCCCCCCCC
Molecular Formula
C26H38N4O
Molecular Weight
422.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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