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AGI-24512

CAT: 0931-T14141-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T14141-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2201066-53-5
Target
Methionine Adenosyltransferase (MAT) |||DNA
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair
Purity
0.9855
Bioactivity
AGI-24512 is a potent inhibitor of methionine adenylyltransferase 2? (MAT2A) (IC50: 8 nM) .AGI-24512 shows antiproliferative activity in MTAP-deficient cancer cells.AGI-24512 inhibits MAT2A, which causes DNA damage in MTAP, and is often used in conjunction with anticancer compounds in cancer research.
Smiles
Cc1[nH]c2c(N3CCCCC3)c(nn2c(=O)c1-c1ccc(O)cc1)-c1ccccc1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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