AG-825

• Description:

  AG-825 (Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 (Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer's disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  397.47

• Molecular Formula:

  C19H15N3O3S2

• Notes:

  Research use only, not for human use.

• Receptor:

  EGFR | Apoptosis

• CAS Number:

  149092-50-2