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L-2-Hydroxyglutaric acid disodium

CAT: 0931-T13748-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T13748-01Size:10 mg
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CAS Number
63512-50-5
Target
Endogenous Metabolite, Mitochondrial Metabolism, Histone Demethylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Purity
0.9992
Bioactivity
L-2-Hydroxyglutaric acid disodium ((S) -2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity (Km and Ki of 2.52 mM and 11.13 mM, respectively) .
Smiles
[Na+].[Na+].O[C@@H](CCC([O-])=O)C([O-])=O
Molecular Formula
C5H6Na2O5
Molecular Weight
192.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Sodium (S)-2-hydroxypentanedioate

L-alpha-hydroxyglutaric acid disodium salt is an organic molecular entity. It has a role as an animal metabolite.

CAS Number63512-50-5
PubChem CID56845267
IUPAC Namedisodium;(2S)-2-hydroxypentanedioate
Molecular FormulaC5H6Na2O5
Molecular Weight192.08
Topological Polar Surface Area100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count12
Formal Charge0
Complexity130
SMILES
C(CC(=O)[O-])[C@@H](C(=O)[O-])O.[Na+].[Na+]
InChI
InChI=1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m0../s1
InChIKey
DZHFTEDSQFPDPP-QTNFYWBSSA-L
Chemical Structure
2D Structure
2D structure of Sodium (S)-2-hydroxypentanedioate
CAS: 63512-50-5
CID: 56845267
Formula: C5H6Na2O5
MW: 192.08
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight192.08
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass192.00106185
Monoisotopic Mass192.00106185
Topological Polar Surface Area100 Ų
Heavy Atom Count12
Formal Charge0
Complexity130
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes