GLPG-3221

• Target:

  Others|||CFTR

• Related Pathways:

  Others|||Membrane transporter/Ion channel

• Bioactivity:

  GLPG-3221 can be uesd for the treatment of cystic fibrosis.GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM.

• Smiles:

  C(=O)(N1[C@H]([C@@H](OCC2=C(OC)N=CC(C(F)(F)F)=C2)[C@H]([C@](C)(C)C)[C@H]1C(O)=O)C3=C(C)C=CC=C3)[C@@H]4CCCCO4

• Molecular Formula:

  C30H37F3N2O6

• Molecular Weight:

  578.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2222264-64-2