ZX-29

• Target:

  ALK|||Autophagy|||Apoptosis

• Related Pathways:

  Autophagy|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis

• Purity:

  0.9951

• Bioactivity:

  ZX-29 is a potent and selective inhibitor of ALK with IC50 values of 2.1 nM, 1.3 nM, and 3.9 nM for ALK, ALK [L1196M], and ALK [G1202R] mutations, respectively. It also induces protective autophagy and exhibits antitumor effects.

• Smiles:

  COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1

• Molecular Formula:

  C23H28ClN7O3S

• Molecular Weight:

  518.03

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2254805-62-2