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TL02-59 dihydrochloride

CAT: 0931-T13186L-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T13186L-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2415263-06-6
Target
Apoptosis, Src
Related Pathways
Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Bioactivity
TL02-59 dihydrochloride is an orally active inhibitor of the Src-family kinase Fgr, with an IC50 of 0.03 nM.
Smiles
O=C(C1=CC=C(C)C(OC2=NC=NC3=C2C=C(OC)C(OC)=C3)=C1)NC4=CC=C(CN5CCN(CC5)CC)C(C(F)(F)F)=C4.Cl.Cl
Molecular Formula
C32H36Cl2F3N5O4
Molecular Weight
682.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

TL02-59 dihydrochloride
CAS Number2415263-06-6
PubChem CID146018965
IUPAC Name3-(6,7-dimethoxyquinazolin-4-yl)oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;dihydrochloride
Molecular FormulaC32H36Cl2F3N5O4
Molecular Weight682.6
Topological Polar Surface Area89.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count11
Rotatable Bond Count9
Heavy Atom Count46
Formal Charge0
Complexity923
SMILES
CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=CC(=C(C=C54)OC)OC)C(F)(F)F.Cl.Cl
InChI
InChI=1S/C32H34F3N5O4.2ClH/c1-5-39-10-12-40(13-11-39)18-22-8-9-23(15-25(22)32(33,34)35)38-30(41)21-7-6-20(2)27(14-21)44-31-24-16-28(42-3)29(43-4)17-26(24)36-19-37-31;;/h6-9,14-17,19H,5,10-13,18H2,1-4H3,(H,38,41);2*1H
InChIKey
WLZPBFIIZXYWTD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of TL02-59 dihydrochloride
CAS: 2415263-06-6
CID: 146018965
Formula: C32H36Cl2F3N5O4
MW: 682.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight682.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count11
Rotatable Bond Count9
Exact Mass681.2096445
Monoisotopic Mass681.2096445
Topological Polar Surface Area89.1 Ų
Heavy Atom Count46
Formal Charge0
Complexity923
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
GTR19204606-01TL02-59 dihydrochloride
HY-112852ATL02-59 (dihydrochloride)
BA2825-10TL02-59
A20302-200TL02-59 200mg
A20302-10TL02-59 10mg
A20302-25TL02-59 25mg
A20302-100TL02-59 100mg
A20302-50TL02-59 50mg
A20302-5TL02-59 5mg
A20302-1TL02-59 1mg

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