TAK-828F

• Target:

  ROR

• Related Pathways:

  Metabolism

• Bioactivity:

  TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor ?t (ROR?t) inverse agonist, with an IC50 of 1.9 nM and a reporter gene IC50 of 6.1 nM.

• Smiles:

  C(NC=1C=C2C(=C(F)C1)C(C)(C)CC2)(=O)[C@H]3C=4C(CCN3C(=O)[C@H]5C[C@@H](CC(O)=O)C5)=NC(OC)=CC4

• Molecular Formula:

  C28H32FN3O5

• Molecular Weight:

  509.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1854901-94-2