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Sorafenib-d4

CAT: 0931-T12976-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T12976-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1207560-07-3
Target
Ferroptosis, FLT, VEGFR, Apoptosis, Raf, Autophagy
Related Pathways
Tyrosine Kinase/Adaptors, Autophagy, Apoptosis, Angiogenesis, MAPK
Bioactivity
Sorafenib D4 is the deuterium labeled Sorafenib. Sorafenib is an inhibitor of multikinase (Raf-1, B-Raf, and VEGFR-3 IC50s of 6 nM, 20 nM, and 22 nM, respectively) .
Smiles
O(C=1C=C(C(NC)=O)N=CC1)C2=C(C(=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C(=C2[2H])[2H])[2H])[2H]
Molecular Formula
C21H16ClF3N4O3
Molecular Weight
468.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C