Sorafenib

• Target :

  PDGFR|||c-Kit|||Autophagy|||Raf|||Apoptosis|||VEGFR|||Ferroptosis|||FLT

• Related Pathways :

  Angiogenesis|||Autophagy|||MAPK|||Tyrosine Kinase/Adaptors|||Apoptosis

• Purity :

  0.9989

• Bioactivity :

  Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFR?, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.

• Smiles :

  O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2

• Molecular Formula :

  C21H16ClF3N4O3

• Molecular Weight :

  464.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  284461-73-0