Sorafenib

CAT: 0931-T0093L-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
CAT#:0931-T0093L-01Size:1 mL - 10 mM (in DMSO)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
284461-73-0
Target
PDGFR|||c-Kit|||Autophagy|||Raf|||Apoptosis|||VEGFR|||Ferroptosis|||FLT
Related Pathways
Angiogenesis|||Autophagy|||MAPK|||Tyrosine Kinase/Adaptors|||Apoptosis
Purity
0.9989
Bioactivity
Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFR?, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.
Smiles
O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
Molecular Formula
C21H16ClF3N4O3
Molecular Weight
464.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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