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SMAP-2

CAT: 0931-T12934-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T12934-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1809068-70-9
Target
Kras, Phosphatase, Ras
Related Pathways
MAPK, Metabolism
Bioactivity
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
Smiles
O[C@@H]1[C@H](CCC[C@H]1N1c2ccccc2CCc2ccccc12)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1
Molecular Formula
C27H27F3N2O4S
Molecular Weight
532.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C