SMAP-2

• CAS Number :

  1809068-70-9

• Target :

  Kras|||Phosphatase|||Ras

• Related Pathways :

  MAPK|||Metabolism

• Bioactivity :

  SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A A? scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .

• Smiles :

  O[C@@H]1[C@H](CCC[C@H]1N1c2ccccc2CCc2ccccc12)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1

• Molecular Formula :

  C27H27F3N2O4S

• Molecular Weight :

  532.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C