SMAP-18

• Target:

  Antibacterial

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  SMAP-18, an 18-amino acid residue peptide amide, is a biologically active truncated variant of Sheep myeloid antimicrobial peptide-29 (SMAP-29) . It retains potent antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. Notably, SMAP-18 exhibits increased cell selectivity relative to the parent peptide SMAP-29 due to its reduced hemolytic activity while maintaining its antimicrobial efficacy.

• Smiles:

  [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCCNC(=N)N)N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)=O)=O)C(C)C)=O)CCCCN)=O)CCCCN)=O)C(NCC(N)=O)=O

• Molecular Formula:

  C93H165N35O18

• Molecular Weight:

  2061.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1629248-30-1