(S) -GNE-987

• Target :

  Epigenetic Reader Domain|||PROTACs

• Related Pathways :

  PROTAC|||Chromatin/Epigenetic

• Bioactivity :

  (S) -GNE-987 binds to the BRD4 BD1 (IC50=4 nM) and BD2 (3.9 nM) bromodomains and can be used to design PROTAC-Antibody Conjugate (PAC) .

• Smiles :

  O=C([C@H](C[C@H](O)C1)N1C([C@@H](NC(CCCCCCCCCCNC(C2=C(CS(=O)(C)=O)C=C(C(N(C3=NC=C(F)C=C3F)C4)=C2)C5=CN(C)C(C6=C5C4=CN6)=O)=O)=O)C(C)(C)C)=O)NCC7=CC=C(C(SC=N8)=C8C)C=C7

• Molecular Formula :

  C56H67F2N9O8S2

• Molecular Weight :

  1096.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C