Plevitrexed

• CAS Number :

  153537-73-6

• Target :

  Others|||DNA/RNA Synthesis

• Related Pathways :

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others

• Bioactivity :

  Plevitrexed is taken up via the ?-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM) . Plevitrexed is used for gastric cancer in clinical.

• Smiles :

  O=C1C=2C(=CC(C)=C(CN(CC#C)C3=CC(F)=C(C(N[C@@H](CCC=4NN=NN4)C(O)=O)=O)C=C3)C2)NC(C)=N1

• Molecular Formula :

  C26H25FN8O4

• Molecular Weight :

  532.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C