Plevitrexed

CAT: 0931-MF-0025766-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0025766-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
153537-73-6
Target
Others|||DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others
Bioactivity
Plevitrexed is taken up via the ?-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM) . Plevitrexed is used for gastric cancer in clinical.
Smiles
O=C1C=2C(=CC(C)=C(CN(CC#C)C3=CC(F)=C(C(N[C@@H](CCC=4NN=NN4)C(O)=O)=O)C=C3)C2)NC(C)=N1
Molecular Formula
C26H25FN8O4
Molecular Weight
532.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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