Products for Research Use Only
RegisterLogin

AZD3458

CAT: 0931-T12466-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T12466-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2132961-46-5
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
AZD3458 is a potent and highly selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ with pIC50s of 9.1, 5.1, <4.5, and 6.5, respectively) .
Smiles
C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1sc(NC(C)=O)nc1C
Molecular Formula
C20H23N3O4S2
Molecular Weight
433.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

(S)-N-(5-(2-(1-cyclopropylethyl)-7-(methylsulfonyl)-1-oxoisoindolin-5-yl)-4-methylthiazol-2-yl)acetamide
CAS Number2132961-46-5
PubChem CID134611894
IUPAC NameN-[5-[2-[(1S)-1-cyclopropylethyl]-7-methylsulfonyl-1-oxo-3H-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
Molecular FormulaC20H23N3O4S2
Molecular Weight433.5
XLogP2
Topological Polar Surface Area133
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity779
SMILES
CC1=C(SC(=N1)NC(=O)C)C2=CC3=C(C(=C2)S(=O)(=O)C)C(=O)N(C3)[C@@H](C)C4CC4
InChI
InChI=1S/C20H23N3O4S2/c1-10-18(28-20(21-10)22-12(3)24)14-7-15-9-23(11(2)13-5-6-13)19(25)17(15)16(8-14)29(4,26)27/h7-8,11,13H,5-6,9H2,1-4H3,(H,21,22,24)/t11-/m0/s1
InChIKey
PAQUFWFUOVDUIO-NSHDSACASA-N
Chemical Structure
2D Structure
2D structure of (S)-N-(5-(2-(1-cyclopropylethyl)-7-(methylsulfonyl)-1-oxoisoindolin-5-yl)-4-methylthiazol-2-yl)acetamide
CAS: 2132961-46-5
CID: 134611894
Formula: C20H23N3O4S2
MW: 433.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight433.5
XLogP32
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass433.11299857
Monoisotopic Mass433.11299857
Topological Polar Surface Area133 Ų
Heavy Atom Count29
Formal Charge0
Complexity779
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T14375-01AZD3988
T1957-01AZD2858
T4249-01AZD3759 hydrochloride

Alternative Products

CatalogName
462363AZD3458

Popular Products