Oxidopamine hydrobromide

• Target:

  Dopamine Receptor|||Autophagy|||Mitophagy

• Related Pathways:

  GPCR/G Protein|||Autophagy|||Neuroscience

• Purity:

  0.9988

• Bioactivity:

  Oxidopamine hydrobromide (6-OHDA hydrobromide) is a widely used neurotoxin and an antagonist of the neurotransmitter dopamine. It selectively destroys dopaminergic neurons, promotes COX-2 activation, induces PGE2 synthesis, and stimulates the secretion of the pro-inflammatory cytokine IL-1?. It is commonly used to establish animal models of Parkinson’s disease (PD) .

• Smiles:

  Br.NCCc1cc (O) c (O) cc1O

• Molecular Formula:

  C8H12BrNO3

• Molecular Weight:

  250.09

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  636-00-0