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Rociletinib hydrobromide

CAT: 0931-T14993-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T14993-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1446700-26-0
Target
EGFR, Others
Related Pathways
JAK/STAT signaling, Others, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT) .
Smiles
Br.COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O
Molecular Formula
C27H29BrF3N7O3
Molecular Weight
636.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C