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Mutant IDH1-IN-2

CAT: 0931-T12128-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T12128-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1429176-69-1
Target
Isocitrate Dehydrogenase (IDH)
Related Pathways
Metabolism
Purity
0.9988
Bioactivity
Mutant IDH1-IN-2 is an inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with an IC50 of 16.6 nM in fluorescence biochemical assay and an IC50 of <22 nM in LS-MS biochemical assay.
Smiles
CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CN3CCC(F)(F)CC3)cc2)n1
Molecular Formula
C24H31F2N5O2
Molecular Weight
459.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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