Levosulpiride

Chemical Information
(S)-(-)-sulpiride is an optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 M at D2, D3, D4, D1 and D5 receptors respectively). It has a role as an antidepressant, an antipsychotic agent, a dopaminergic antagonist and an antiemetic. It is an enantiomer of a (R)-(+)-sulpiride.
| CAS Number | 23672-07-3 |
| PubChem CID | 688272 |
| IUPAC Name | N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide |
| Molecular Formula | C15H23N3O4S |
| Molecular Weight | 341.4 |
| XLogP | 0.6 |
| Topological Polar Surface Area | 110 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 6 |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 505 |
| Property | Value |
|---|---|
| Molecular Weight | 341.4 |
| XLogP3 | 0.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 6 |
| Exact Mass | 341.14092740 |
| Monoisotopic Mass | 341.14092740 |
| Topological Polar Surface Area | 110 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 505 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
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