Levosulpiride

• Description :

  Levosulpiride (RV-12309) is the (S) -enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class.

• Product Name Alternative :

  RV-12309; S- (-) -Sulpiride

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Metabolic Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Levosulpiride.html

• Purity :

  99.87

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(NC[C@H]1N(CC)CCC1)C2=CC(S(=O)(N)=O)=CC=C2OC

• Molecular Formula :

  C15H23N3O4S

• Molecular Weight :

  341.43

• References & Citations :

  [1]Arif ST, et al., Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice. Pharmaceuticals (Basel) . 2023 Aug 29;16 (9) :1220.|[2]Akrab SNA, et al., The role of mosapride and levosulpiride in gut function and glycemic control in diabetic rats. Arab J Gastroenterol. 2023 May;24 (2) :109-116.|[3]Tonini M, et al., 5-HT4 receptors contribute to the motor stimulating effect of levosulpiride in the guinea-pig gastrointestinal tract. Dig Liver Dis. 2003 Apr;35 (4) :244-50.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [23672-07-3]