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M8891

CAT: 0931-T11930-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T11930-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1464842-09-8
Target
Others, Aminopeptidase
Related Pathways
Metabolism, Others
Bioactivity
M8891 is an orally active, reversible, and brain-penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor (IC50: 54 nM; Ki: 4.33 nM) . It inhibits the growth of primary endothelial cells and tumor cells, demonstrating both antiangiogenic and antitumoral activity.
Smiles
O[C@@]1(CCN(C1=O)c1ccc2[nH]ccc2c1)C(=O)NCc1cc(F)cc(F)c1
Molecular Formula
C20H17F2N3O3
Molecular Weight
385.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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