(R) -M8891

CAT: 0804-HY-133016A-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-133016A-01Size:5 mg

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Description

(R) -M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor[1].

CAS Number

2575547-29-2

UNSPSC

12352005

Target

MetAP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-m8891.html

Purity

98.67

Solubility

DMSO : 140 mg/mL (ultrasonic)

Smiles

O=C([C@@]1(O)C(N(C2=CC3=C(NC=C3)C=C2)CC1)=O)NCC4=CC(F)=CC(F)=C4

Molecular Formula

C20H17F2N3O3

Molecular Weight

385.36

References & Citations

[1]Timo Heinrich, et al. Process for manufacturing (s) -3-hydroxy-1- (1h-indol-5-yl) -2-oxo-pyrrolidine-3-carboxylic acid 3,5-difluoro-benzylamide. WO2021001328A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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BA7971-1	M8891

(R) -M8891

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