LY 222306

• Target:

  DHFR|||Antifolate

• Related Pathways:

  Metabolism|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity:

  LY 222306, a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor, has a Ki of 0.77 nM.

• Smiles:

  O=C1C2=C(NCC(CCC=3OC(C(N[C@@H](CCC(O)=O)C(O)=O)=O)=CC3)C2)NC(N)=N1

• Molecular Formula:

  C19H23N5O7

• Molecular Weight:

  433.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  154446-98-7