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Lanraplenib

CAT: 0931-T11824LL-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11824LL-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1800046-95-0
Target
Syk
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9942
Bioactivity
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) being developed for treating inflammatory diseases. It inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
Smiles
Nc1cncc(n1)-c1cn2ccnc2c(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1
Molecular Formula
C23H25N9O
Molecular Weight
443.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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