Imatinib-d8

• Target:

  C-Kit|||PDGFR|||SARS-CoV|||Autophagy|||Bcr-Abl

• Related Pathways:

  Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Autophagy|||Microbiology/Virology|||Angiogenesis

• Bioactivity:

  Imatinib-d8 (STI571 D8) is a 2H-labeled version of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with anti-tumor activity, selectively inhibiting BCR-ABL, v-Abl, PDGFR, c-kit kinases, and is used in chronic myeloid leukemia treatment.

• Smiles:

  N (C=1N=C (C=CN1) C=2C=CC=NC2) C3=CC (NC (=O) C4=CC=C (CN5C (C (N (C) C (C5 ([2H]) [2H]) ([2H]) [2H]) ([2H]) [2H]) ([2H]) [2H]) C=C4) =CC=C3C

• Molecular Formula:

  C29H23D8N7O

• Molecular Weight:

  501.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1092942-82-9