Imatinib-d8

• Target:

  C-Kit|||PDGFR|||SARS-CoV|||Autophagy|||Bcr-Abl

• Related Pathways:

  Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Autophagy|||Microbiology/Virology|||Angiogenesis

• Bioactivity:

  Imatinib-d8 (STI571 D8) is a 2H-labeled version of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with anti-tumor activity, selectively inhibiting BCR-ABL, v-Abl, PDGFR, c-kit kinases, and is used in chronic myeloid leukemia treatment.

• Smiles:

  N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=CC(NC(=O)C4=CC=C(CN5C(C(N(C)C(C5([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C=C4)=CC=C3C

• Molecular Formula:

  C29H23D8N7O

• Molecular Weight:

  501.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1092942-82-9