Hck-IN-1

CAT: 0931-T11538-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T11538-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1473404-51-1

Target

Src, Hck, HIV Protease

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Proteases/Proteasome, Microbiology/Virology

Purity

0.9907

Bioactivity

Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for wild-type HIV-1 replication.

Smiles

NC(=S)n1nc(c(\N=N\c2cccc(Cl)c2)c1O)-c1ccc(cc1)[N+]([O-])=O

Molecular Formula

C16H11ClN6O3S

Molecular Weight

402.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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E2834-5mg	Hck-IN-1
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