H3B-6545

• Target :

  Estrogen Receptor/ERR|||Estrogen/progestogen Receptor

• Related Pathways :

  Endocrinology/Hormones

• Bioactivity :

  H3B-6545 is a selective estrogen receptor covalent antagonist (SERCA) that is orally available. As a novel class of ER? antagonists, H3B-6545 is used in the study of metastatic breast cancers, such as estrogen receptor-positive (ER), human epidermal growth factor receptor 2-negative (HER2-) breast cancer.

• Smiles :

  C(=C(\CC(F)(F)F)/C1=CC=CC=C1)(\C=2C=C3C(=CC2)NN=C3F)/C=4C=CC(OCCNC/C=C/C(N(C)C)=O)=NC4

• Molecular Formula :

  C30H29F4N5O2

• Molecular Weight :

  567.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2052130-80-8