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GSK-1070916

CAT: 0931-T6129-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6129-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
942918-07-2
Target
AMPK, Tie-2, Aurora Kinase, FLT, Apoptosis
Related Pathways
Apoptosis, Chromatin/Epigenetic, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Angiogenesis, PI3K/Akt/mTOR signaling
Purity
0.9973
Bioactivity
GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
Smiles
CCn1cc(c(n1)-c1ccc(NC(=O)N(C)C)cc1)-c1ccnc2[nH]c(cc12)-c1cccc(CN(C)C)c1
Molecular Formula
C30H33N7O
Molecular Weight
507.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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