GNE-1858

• Target :

  MAPK

• Related Pathways :

  MAPK

• Purity :

  0.9936

• Bioactivity :

  GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA) .

• Smiles :

  CC(C)n1ncc2cnc(Nc3cc(nc(n3)N3CCC(F)(F)C3)C3CCNC3)cc12

• Molecular Formula :

  C21H26F2N8

• Molecular Weight :

  428.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2680616-96-8