Gefitinib-d8

CAT: 0931-T11384Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T11384Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

857091-32-8

Target

EGFR, Autophagy

Related Pathways

Autophagy, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Bioactivity

Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.

Smiles

[2H]C1([2H])OC([2H])([2H])C([2H])([2H])N(CCCOc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2OC)C1([2H])[2H]

Molecular Formula

C22H24ClFN4O3

Molecular Weight

454.95

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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