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Beclometasone dipropionate

CAT: 0931-T1127-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0931-T1127-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5534-09-8
Target
ROS, Glucocorticoid Receptor, Reactive Oxygen Species, NO Synthase
Related Pathways
Metabolism, Immunology/Inflammation, Endocrinology/Hormones, NF-κB
Purity
0.9944
Bioactivity
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
Smiles
[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)C1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Molecular Formula
C28H37ClO7
Molecular Weight
521.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C