Beclometasone dipropionate (Standard)

Beclometasone dipropionate (Standard)

• CAS Number: 5534-09-8
• UNSPSC Description: Beclometasone dipropionate (Standard) is the analytical standard of Beclometasone dipropionate. This product is intended for research and analytical applications. Beclometasone dipropionate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate can be used for asthma [1][2].
• Target Antigen: Glucocorticoid Receptor; NO Synthase; Reactive Oxygen Species
• Type: Reference Standards
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Vitamin D Related/Nuclear Receptor
• Field of Research: Inflammation/Immunology; Endocrinology
• Assay Protocol: https://www.medchemexpress.com/beclometasone-dipropionate-standard.html
• Smiles: C[C@@]12[C@](C[C@H](C)[C@]2(OC(CC)=O)C(COC(CC)=O)=O)([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C1)=O
• Molecular Weight: 521.04
• References & Citations: [1]Hrvacić B, et, al. Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma. Pharm Res. 2006 Aug;23(8):1765-75. |[2]Montalbano AM, et, al. Beclomethasone dipropionate and formoterol reduce oxidative/nitrosative stress generated by cigarette smoke extracts and IL-17A in human bronchial epithelial cells. Eur J Pharmacol. 2013 Oct 15;718(1-3):418-27.
• Shipping Conditions: Room Temperature