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DZ2002

CAT: 0931-T11134-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11134-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
33231-14-0
Target
Antibacterial, Antibiotic, Akt, NF-κB, MEK, ERK, STAT, Others, PI3K
Related Pathways
JAK/STAT signaling, Cytoskeletal Signaling, MAPK, NF-κB, PI3K/Akt/mTOR signaling, Others, Microbiology/Virology, Stem Cells
Purity
0.9991
Bioactivity
DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity. It effectively prevents experimental dermal fibrosis by reversing the profibrotic phenotype in multiple cell types, making it useful for studying autoimmune diseases like lupus syndrome and systemic sclerosis.
Smiles
COC(=O)C(O)CCn1cnc2c(N)ncnc12
Molecular Formula
C10H13N5O3
Molecular Weight
251.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

9H-Purine-9-butanoic acid, 6-amino-alpha-hydroxy-, methyl ester
CAS Number33231-14-0
PubChem CID11658872
IUPAC Namemethyl 4-(6-aminopurin-9-yl)-2-hydroxybutanoate
Molecular FormulaC10H13N5O3
Molecular Weight251.24
XLogP-0.5
Topological Polar Surface Area116
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count18
Formal Charge0
Complexity303
SMILES
COC(=O)C(CCN1C=NC2=C(N=CN=C21)N)O
InChI
InChI=1S/C10H13N5O3/c1-18-10(17)6(16)2-3-15-5-14-7-8(11)12-4-13-9(7)15/h4-6,16H,2-3H2,1H3,(H2,11,12,13)
InChIKey
HNKGMGPCSSJYOT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 9H-Purine-9-butanoic acid, 6-amino-alpha-hydroxy-, methyl ester
CAS: 33231-14-0
CID: 11658872
Formula: C10H13N5O3
MW: 251.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight251.24
XLogP3-0.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass251.10183929
Monoisotopic Mass251.10183929
Topological Polar Surface Area116 Ų
Heavy Atom Count18
Formal Charge0
Complexity303
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BUP12911-01DZ2002
A20912-100DZ2002 100mg
A20912-5DZ2002 5mg
A20912-50DZ2002 50mg
A20912-10DZ2002 10mg
HY-18620RDZ2002 (Standard)
A20912-500DZ2002 500mg
A20912-25DZ2002 25mg
A20912-1DZ2002 1mg
A20912-10mM-DDZ2002 10mM * 1mL in DMSO

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