DZ2002

CAT:
931-T11134-01
Size:
1 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
DZ2002 - image 1

DZ2002

  • CAS Number :

    33231-14-0
  • Target :

    Antibacterial|||Antibiotic|||Akt|||NF-?B|||MEK|||ERK|||STAT|||Others|||PI3K
  • Related Pathways :

    JAK/STAT signaling|||Cytoskeletal Signaling|||MAPK|||NF-?B|||PI3K/Akt/mTOR signaling|||Others|||Microbiology/Virology|||Stem Cells
  • Purity :

    0.9991
  • Bioactivity :

    DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity. It effectively prevents experimental dermal fibrosis by reversing the profibrotic phenotype in multiple cell types, making it useful for studying autoimmune diseases like lupus syndrome and systemic sclerosis.
  • Smiles :

    COC(=O)C(O)CCn1cnc2c(N)ncnc12
  • Molecular Formula :

    C10H13N5O3
  • Molecular Weight :

    251.24
  • Shipping Conditions :

    Cool pack
  • Storage Temperature :

    -20°C

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