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DZ2002 (Standard)

CAT: 0804-HY-18620RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18620RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DZ2002 (Standard) is the analytical standard of DZ2002. This product is intended for research and analytical applications. DZ2002 is an orally active, reversible and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), with good immunosuppressive activity. DZ2002 prevents the development of experimental dermal fibrosis by reversing the profibrotic phenotype of various cell types. DZ2002 can be used in studies of autoimmune diseases such as lupus syndrome and systemic sclerosis[1][2].
CAS Number
33231-14-0
UNSPSC
12352100
Target
Akt; Antibiotic; Bacterial; ERK; MEK; NF-κB; PI3K; Reference Standards; STAT
Related Pathways
Anti-infection; JAK/STAT Signaling; MAPK/ERK Pathway; NF-κB; Others; PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
OC(C(OC)=O)CCN1C(N=CN=C2N)=C2N=C1
Molecular Formula
C10H13N5O3
Molecular Weight
251.25
References & Citations
[1]Wu QL, et al. Inhibition of S-adenosyl-L-homocysteine hydrolase induces immunosuppression. J Pharmacol Exp Ther. 2005 May;313 (2) :705-11. |[2]Zhang Z, et al. DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models. Arthritis Res Ther. 2019 Dec 16;21 (1) :290.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
T11134-01DZ2002
A20912-100DZ2002 100mg
A20912-5DZ2002 5mg
A20912-50DZ2002 50mg
A20912-10DZ2002 10mg
A20912-500DZ2002 500mg
A20912-25DZ2002 25mg
A20912-1DZ2002 1mg
A20912-10mM-DDZ2002 10mM * 1mL in DMSO
abx098968-01Standard

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