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DGN462

CAT: 0931-T11017-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T11017-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1394079-41-4
Target
ADC Cytotoxin, DNA Alkylator/Crosslinker
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
DGN462 is an effective DNA alkylating agent with anti-tumor activity, as in acute myeloid leukemia (AML) . DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
Smiles
O=C1N2C=3C(C[C@]2(CNC=4C1=CC(OC)=C(OCC5=CC(N(CCOCCOCCOC)CC(C)(C)S)=CC(COC6=C(OC)C=C7C(=C6)N=C[C@]8(N(C7=O)C=9C(C8)=CC=CC9)[H])=C5)C4)[H])=CC=CC3
Molecular Formula
C53H59N5O9S
Molecular Weight
942.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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